Publications

Evaluation of plasma sphingolipids as mediators of the relationship between kidney disease and cardiovascular events

Authors: Lidgard B, Bansal N, Zelnick LR, Hoofngale A, Fretts AM, Longstreth Jr WT, Shlipak MG, Siscovick DS, Umans JG, Lemaitre RN

Citation: EBioMedicine. 2023 Aug 24;95:104765.

PMID: 37634384 | Journal / Book: EBioMedicine


Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia

Authors: Deem JD, Tingley D, Bjerregaard AM, Secher A, Chan O, Uzo C, Richardson N, Giering E, Doan T, Phan BA, Wu B, Scarlett JM, Morton GJ, Schwartz MW

Citation: Diabetes . 2023 Jun 22 online ahead of print

PMID: 37347793 | Journal / Book: Diabetes


2021 George Lyman Duff Memorial Lecture: The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease

Authors: Bornfeldt K

Citation: Arterioscler Thromb Vasc Biol. 2022 Jul; 42(7): 819–830

PMID: 35616031 | Journal / Book: Arterioscler Thromb Vasc Biol


Metabolism and pharmacokinetics of vitamin D in patients with cystic fibrosis

Authors: Bergagnini-Kolev MC, Hsu S, Aitken ML, Goss CH, Hoofnagle AN, Zelnick LR, Lum D, Best CM, Thummel KE, Kestenbaum BR, de Boer IH, Lin YS

Citation: J Steroid Biochem Mol Biol. 2023 May 20;232:106332.

PMID: 37217104 | Journal / Book: J Steroid Biochem Mol Biol


Warm responsive neurons in the hypothalamic preoptic area are potent regulators of glucose homeostasis in male mice

Authors: Deem, JD, Phan BA, Ogimoto K, Cheng A, Bryan CL, Scarlett JM, Schwartz MW, Morton GJ

Citation: Endocrinology. 2023 Jun 6;bqad074

PMID: 37279930 | Journal / Book: Endocrinology


Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice

Authors: Dorfman M, Monfeuga T, Melhorn S, Kanter J, Frey J, Fasnacht R, Chandran A, Lala E, Velasco I, Rubinow K, Meek T, Schur E, Bornfeldt K, Thaler J

Citation: Am J Physiol Endocrinol Metab . 2023 May 1;324(5):E461-E475.

PMID: 37053049 | Journal / Book: Am J Physiol Endocrinol Metab


Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexia

Authors: Herodes M, Anderson LJ, Shober S, Schur EA, Graf SA, Ammer N, Ramiro S, Marcelli M, Garcia JM

Citation: J Cachexia Sarcopenia Muscle. Online ahead of print.

PMID: 36860137 | Journal / Book: J Cachexia Sarcopenia Muscle


Apolipoprotein C3 induces inflammasome activation only in its delipidated form

Authors: Hsu CC, Shao B, Kanter JE, He Y, Vaiser T, Witztum JL, Snell-Bergeon J, McInnes G, Bruse S, Gottesman O, Mullick AE, Bornfeldt KE

Citation: Nat Immunol. 2023 Mar; 24(3): 408–411.

PMID: 36781985 | Journal / Book: Nat Immunol


High-Density Lipoprotein Lipidomics in Chronic Kidney Disease

Authors: Lidgard B, Hoofnagle AN, Zelnick LR, de Boer IH, Fretts AM, Kestenbaum BR, Lemaitre RN, Robinson-Cohen C, Bansal N.

Citation: Clin Chem. 2023 Jan 16;hvac216.

PMID: 36644946 | Journal / Book: Clin Chem.


The plasma free fraction of 25-hydroxyvitamin D3 is not strongly associated with 25-hydroxyvitamin D3 clearance in kidney disease patients and controls

Authors: Best CM, Thummel KE, Hsu S, Lin Y, Zelnick LR, Kestenbaum B, Kushnir MM, de Boer IH, Hoofnagle AN.

Citation: J Steroid Biochem Mol Biol. 2023 Feb;226:106206

PMID: 36404469 | Journal / Book: J Steroid Biochem Mol Biol.


Biomarkers of Vitamin D Metabolism and Hip and Vertebral Fracture Risk: The Multi‐Ethnic Study of Atherosclerosis

Authors: Hsu S, Criqui MH, Ginsberg C, Hoofnagle AN, Ix JH, McClelland RL, Michos ED, Shea SJ, Siscovick D, Zelnick LR, Kestenbaum BR, de Boer IH.

Citation: JBMR Plus. 2022 Dec; 6(12): e10697.

PMID: 36530185 | Journal / Book: JBMR Plus


Tubular Secretion and Estimated GFR Decline in the Jackson Heart Study

Authors: Granda ML, Zelnick LR, Prince DK, Hoofnagle A, Young BA, Kestenbaum BR, JHS Study Investigators.

Citation: Kidney Int Rep. 2022 Dec; 7(12): 2668–2675.

PMID: 36506244 | Journal / Book: Kidney Int Rep.


Association of Proximal Tubular Secretory Clearance with Long-Term Decline in Cognitive Function

Authors: Lidgard B, Bansal N, Zelnick LR, Hoofngale A, Chen J, Colaizzo D, Dobre M, Mills KT, Porter AC, Rosas SE, Sarnak MJ, Sliger S, Sondheimer J, Tamura MK, Yaffe K, Kestenbaum B, CRIC Study Investigators.

Citation: J Am Soc Nephrol. 2022 Jul;33(7):1391-1401

PMID: 35444055 | Journal / Book: J Am Soc Nephrol


Kidney Tubular Injury Biomarkers and Secretory Function in Acute Decompensated Heart Failure

Authors: Kula AJ, Prince DK, Kestenbaum BR, Song L, O’Brien KD, Bansal N.

Citation: Kidney Med. 2022 Jan 25; 4(3).

PMID: 35386601 | Journal / Book: Kidney Med


Circulating ceramides and sphingomyelins and the risk of incident cardiovascular disease among people with diabetes: the strong heart study.

Authors: Jensen P, Fretts AM, Hoofnagle AN, McKnight B, Howard BV, Uman JG, Sitlani CM, Siscovick DS, King IB, Sotoodehnia N, Lemaitre RN.

Citation: Cardiovasc Diabetol. 2022; 21: 167.

PMID: 36042511 | Journal / Book: Cardiovasc Diabetol


Assessment of kidney proximal tubular secretion in critical illness

Authors: Bhatraju PK, Chai XY, Sathe NA, Ruzinski J, Siew ED, Himmelfarb J, Hoofnagle AN, Wurfel MM, Kestenbaum BR.

Citation: JCI Insight. 2021 May 24; 6(10): e145514.

PMID: 33886506 | Journal / Book: JCI Insight


The Multi-Ethnic Study of Atherosclerosis individual response to vitamin D trial: Building a randomized clinical trial into an observational cohort study

Authors: de Boer IH, Prince DK, Williams K, Allen NB, Burke GL, Hoofnagle AN, Hsu S, Li X, Liu KJ, McClelland RL, Michos ED, Psaty BM, Shea SJ, Rice KM, Rotter JI, Siscovick D, Tracy RP, Watson KE, Kestenbaum BR.

Citation: Contemp Clin Trials. 2021 Apr; 103: 106318.

PMID: 33588078 | Journal / Book: Contemp Clin Trials


Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study

Authors: Chen Y, Zelnick LR, Huber MP, Wang K, Bansal N, Hoofnagle AN, Paranji RK, Heckbert SR, Weiss NS, Go AS, Hsu C-Y, Feldman HI, Waikar SS, Mehta RC, Srivastava A, Seliger SL, Lash JP, Porter AC, Raj DS, Kestenbaum BR, CRIC Study Investigagtors.

Citation: Am J Kidney Dis. 2021 Aug; 78(2): 226–235.e1.

PMID: 33421453 | Journal / Book: Am J Kidney Dis


Prediction of Kidney Drug Clearance: A Comparison of Tubular Secretory Clearance and Glomerular Filtration Rate

Authors: Chen Y, Zelnick LR, Wang K, Hoofnagle AN, Yeung CK, Shireman LM, Phillips B, Brauchla CC, de Boer I, Manahan L, Heckbert SR, Himmelfarb J, Kestenbaum BR.

Citation: J Am Soc Nephrol. 2021 Feb; 32(2): 459–468.

PMID: 33239392 | Journal / Book: J Am Soc Nephrol.


Differences in 25-Hydroxyvitamin D Clearance by eGFR and Race: A Pharmacokinetic Study

Authors: Hsu S, Zelnick LR, Lin YS, Best CM, Kestenbaum BR, Thummel KE, Hoofnagle AN, de Boer IH.

Citation: J Am Soc Nephrol. 2021 Jan; 32(1): 188–198.

PMID: 33115916 | Journal / Book: J Am Soc Nephrol